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Topic M438 - Dutasteride - forum # 10

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Re: Type 1 5 alpha reductase

From: RSanders
Date: 12 Jul 2001
Time: 14:13:16
Remote Name: 128.151.144.51

Comments

>>Which is it 70% or 100% inhibition of type 2 5AR?<<

<<I already told you that! 100%! Which part of my explanation did you not understand??>>

I wonder about this; a patient-to-patient variation in type II 5AR inhibition by finasteride might explain the drug's failure to maintain hair counts in roughly 1 out of 5 people. Just a thought, but perhaps it's due to varying rates of inactivation of the drug by the liver.

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