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Topic M456 - Hair Multiplication & Other Advanced Treatments (forum # 41)

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in vitro method for HM?

From: James Bond
Date: 06 Aug 2001
Time: 02:16:31
Remote Name: 63.10.223.220

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Well, I have been doing some research today and I have been uncovering some right things about my theory and some wrong things. There is a plethora of new research in this area, but the bulk of it is in pay per view articles, so I'm working around the edges.

Along the way I found this and thought it might be of interest. Notice the last sentence. Oh I have also found some very interesting things about follicle stem cells and the telegon to anagen remodeling process, but I'm still researching this area.

Controls of hair follicle cycling.

Stenn KS, Paus R.

Beauty Genome Sciences Inc., Skillman, New Jersey, USA. kstenn@cpcus.jnj.com

Nearly 50 years ago, Chase published a review of hair cycling in which he detailed hair growth in the mouse and integrated hair biology with the biology of his day. In this review we have used Chase as our model and tried to put the adult hair follicle growth cycle in perspective. We have tried to sketch the adult hair follicle cycle, as we know it today and what needs to be known. Above all, we hope that this work will serve as an introduction to basic biologists who are looking for a defined biological system that illustrates many of the challenges of modern biology: cell differentiation, epithelial-mesenchymal interactions, stem cell biology, pattern formation, apoptosis, cell and organ growth cycles, and pigmentation. The most important theme in studying the cycling hair follicle is that the follicle is a regenerating system. By traversing the phases of the cycle (growth, regression, resting, shedding, then growth again), the follicle demonstrates the unusual ability to completely regenerate itself. The basis for this regeneration rests in the unique follicular epithelial and mesenchymal components and their interactions. Recently, some of the molecular signals making up these interactions have been defined. They involve gene families also found in other regenerating systems such as fibroblast growth factor, transforming growth factor-beta, Wnt pathway, Sonic hedgehog, neurotrophins, and homeobox. For the immediate future, our challenge is to define the molecular basis for hair follicle growth control, to regenerate a mature hair follicle in vitro from defined populations, and to offer real solutions to our patients' problems.

Publication Types: Review Review, tutorial

PMID: 11152763 [PubMed - indexed for MEDLINE]

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From: online poker
Date: 08 Mar 2006
Time: 05:52:57
Remote Name: 218.131.196.147

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From: cheap meridia no prescription
Date: 09 Jan 2008
Time: 05:59:43
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